Arwa Alshoaibi
مشرفـة عـامـة
كيف تعرفت علينا : ............
الكــلــيــة : ........
القسم ( التخصص ) : .......
السنة الدراسية (المستوى الدراسي) : .......
الجنس : 
عدد الرسائل : 12959
العمر : 35
الدوله : بعيييييييييييييييييييييييييييييد
العمل/الترفيه : القراءه والاطلاع على كل جديد
المزاج : متقلب المزاج
نقاط : 18850
تاريخ التسجيل : 16/04/2010
: :قائمة الأوسمة : :
بطاقة الشخصية
التقييم: 10
 |  موضوع: Ceruloplasmin  الأحد ديسمبر 26, 2010 4:46 pm | |
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Ceruloplasmin
(Cp) is an α2-globulin that binds copper for transport within the
circulation after it is absorbed from the gastrointestinal tract. Among
the disorders associated with abnormal ceruloplasmin levels is Wilson’s
disease (hepatolenticular degeneration), an inherited disorder
characterized by excessive absorption of copper from the
gastrointestinal tract, decreased ceruloplasmin, and deposition of
copper in the liver, brain, corneas (Kayser-Fleischer rings), and
kidneys. In addition to low ceruloplasmin levels, serum copper levels
are decreased because of excessive excretion of unbound copper in the
kidneys and deposition of copper in the body tissues. The disorder
manifests during the first three decades of life and is fatal unless
treatment is instituted.
Reference Values
Newborns 2–13 mg/dL
Adults 23–50 mg/dL
INDICATIONS FOR CERULOPLASMIN TEST
-Family history of Wilson’s disease (hepatolenticular degeneration)
-Signs
of liver disease combined with neurological changes, especially in a
young person, with Wilson’s disease indicated by decreased levels
-Monitoring of ceruloplasmin levels in disorders associated with abnormal values
-Monitoring of response to TPN (hyperalimentation), which may lead to decreased levels?
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