Contemporary Drug Synthesis

Contemporary Drug Synthesis By Jie Jack Li, Douglas S. Johnson, Drago R. Sliskovic, Bruce D. Roth
Publisher: Wi.,.ley-Int..ers..cience 2004 | 240 Pages | ISBN: 0471214809 | PDF | 4 MB

An integrated and insightful look at successful drug synthesis in today's drug discovery market
The pharmaceutical industry is unquestionably vibrant today, with drug
synthesis making a vital contribution. Whether in the early
developmental stages of identifying and optimizing a lead, or the latter
stages of process development and cost-effective scale-up, the ability
to design elegant and economical synthetic routes is often a major
factor in the eventual viability and commercial success of a drug.
Contemporary Drug Synthesis examines how leading researchers and
manufacturers have integrated chemistry, biology, pharmacokinetics, and a
host of other disciplines in the creation and development of leading
drugs.
Authored by four of the pharmaceutical industry's most respected scientists, this timely volume:

Focuses on the processes that resulted in high-profile drugs
including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over
a dozen others
Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis
Organizes the drugs into fourteen therapeutic areas for clarity and ease of use
Process chemists provide an essential bridge between chemistry
and the marketplace, creating scientifically practical drug processes
while never losing sight of the commercial viability of those processes.

Contemporary Drug Synthesis meets the needs of a growing
community of researchers in pharmaceutical research and development, and
is both a useful guide for practicing pharmaceutical scientists and an
excellent text for medicinal and organic chemistry students.

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