50 سؤال

موضوع: 50 سؤال الأربعاء يونيو 23, 2010 4:21 am

50 سؤال من أسئلة البيوكمستري :
حيث يتم عرض السؤال ويليه الإجابة مباشرة دون اختيارات :

[align=left]- Which of the following usually requires concentration before analysis?
- Cerbrospinal fluid for protein electrophoresis.

2- Which of the following situations indicates that an instrument problem is present and requires further investigation ?
- A series of anion gabs

3- A trough blood sample for routine therapeutic drug monitoring is usually obtained ?
- Just before the next scheduled dose

4- The turbid of lipemic serum is due to an elevated level of :
- Triglycerides

5- In a coupled enzymatic method for measuring serum cholesterol the color change observed during the indicator reaction is dependent upon the generation of:- Hydrogen peroxides

6- PH 8.6 is used for serum protein electrophoresis so that :
- All serum proteins will have a net negative charge .

7- When quantitating serum protein using the biuret reaction , the biuret reagent is reacting with :
- Peptide bonds in proteins

8- Which one of the following protein fractions , when separated in serum by electrophoresis on cellulose acetate , contains a single protein ?
- Albumin

9- Osmolality measurements determine the :
- Moles of dissolved solutes per kilogram of solvent

10- When using an automated instrument , the amount of carryover between consecutive samples is not affected by :
- Using a serum plank

11- A serum sample is diluted 1 to 3, 1:3 before analysis and the following results obtained :
Total protein – 4.1 g /dl
Albumin - 1.5 - g/dl

Which total protein concentration should be reported ?
- 12.3 g/dl

12- In an adult , a blood glucose level of 35 mg /dl is :
- Dangerously low

13- Measurements of urinary human chorionic gondotropin (HCG) in men can be used :
- Detect testicular tumors

14- Xanthochromic cerebrospinal fluid is an indicator of:
- Cerebral hemorrhage

15- A creatinine clearance result below the normal reference range most likely indicates a decrease in :
- Renal glomerular filtration

16- A physician suspects that a patient has Cushing syndrome . Based on this information , which of the following tests would assist in this diagnosis ?
- Cortisol level

17- Identify the results that are not in electrolyte balance . ( Results are in mmol/L )
- Na : 145 K : 4.0 CL :90 CO2 :15

18- Which of the following urine specimens is most useful when screening for glucoseuria :
- 2 – hour postprandial specimens

19- What is the longest time that a urine specimen can remain at room temperature before it is no longer considered acceptable for analysis ?
- 2 hour

20- Which of the following situations requires corrective action before proceeding with specimen testing ?
- Reagent strip protein result is trace when using negative control material

21- Which protein test is not able to detect immunoglobulin light chains in urine ?
- Reagent strip protein test .

22- Which of the following sets of the urinalysis results , physical appearance and SG is physiologically possible and indicates a concentrated urine
- SG = 1.030 , Color = yellow

23- Urine sediment that contains red blood cells , red blood cell cast , protein , is characteristic of :
- Acute glomerulonephritis .

24- Hyaline casts are found in increased numbers in the urine sediment
- Following strenuous exercise

25- Which of the following urinalysis findings include contradictory results that should not be reported :]
- PH 6.0 - bilirubin: Positive - ammonium biurate crystals

26- The following crystals are observed in a randomly collected urine specimen with a pH of 7.0 :
- Triple phosphate

27- When present in the urine . which the following substances could cause false- positive reagent strip blood results :
- Myoglobin

28- Which of the following analytes can deteriorate if a blood specimen is exposed to light :
- Bilirubin

29- Which of the following collection tubes is the specimen of choice for the determination of glycated hemoglobin :
- EDTA tube

30- Which of the following serum samples is satisfactory for alkaline phosphatase measurement
- Sample maintained at room temperature for 2 hours .

31- Which of the following changes occurs in a serum specimen that is maintained at 4 C for 8 hours :
- Alkaline phosphatase activity increased

32- A centrifuge is loaded with patient samples and turned on . it begins to vibrate and dance across the table top . which of the following statements best accounts for this observation?
- The tubes are not balanced in the carriers .

33- Which of the following enzymes catalyzes the conversion of glucose to hydrogen peroxide and gluconic acid :
- Glucose oxidase

34- Which of the following constituents has the greatest effect on serum osmolality :
- Sodium

35- When iontophoresis is used to collect sweat for chloride analysis , pilocarpine is used to:
- Induce sweat secretion

36- Which of the following methods is not used to quantitate serum albumin:
- Sulfosalicylic acid (SSA) precipitation

37- If moderately hemolyzed serum specimen is used for protein electrophoresis , which of the following protein fractions will be elevated :
- Beta – globulin

38 – the normal ratio of bicarbonate ion to carbonic acid in arterial blood is :
- 20 : 1

38- Increased serum uric acid is found in each the following conditions except :
- Hypothyroidism

39- If LDL receptors are nonfunctional due to disease .the plasma level of which lipid would increase the most?
- Cholesterol

40- Which of the following enzymes provides the best indication of obstructive liver disease
- Alkaline phosphatase

41- Urine preservation by refrigeration can cause :
- Increased turbidity due to precipitate of solutes .

42- Which of the following tests is not used to assess the kidney ability to concentrate the urine ?
- PH

43- Which of these sugars cannot be detected in urine using the copper reduction test :
- Sucrose

44- All of the following substances can affect the detection of urine glucose using reagent strips except:
- Galactose

45- The presence of waxy casts in urine sediment and a fixed urine SG of 1.010 correlates best with :
- renal failure

46- urine sediment that contains free fat globules and fatty casts is characteristic of:
- the nephritic syndrome .

47- serum total protein results obtained using the biuret reaction can be falsely increased it :
- The specimen is hemolyzed .

48- An enzyme assay that shows substrate depletion should be repeated using :
- Less sample

49- Which of the following urinalysis results is considered " abnormal" clinically significant :
- Bilirubin === small

50- Which of the following terms is considered in appropriate for reporting urine color

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